Grey's Anatomy alum Sara Rami­rez is officially headed for divorce.

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Entertainment Tonight reported Wednesday that Rami­rez, 48, filed for divorce from their husband, Ryan DeBolt, this week.

Rami­rez cited "irreconcilable differences" for the split and listed their date of separation as January 2018.

The news comes nearly three years after Rami­rez announced their split from DeBolt in a since-deleted Instagram post.

"Ryan and I are no longer together," the actor said at the time. "We remain loving and supportive in how we are choosing to forge our new individual paths."

People confirmed Wednesday that Rami­rez has filed for divorce.

Rami­rez and DeBolt married in July 2012 during Rami­rez's run as Dr. Callie Torres on Grey's Anatomy.

Rami­rez has since played Kat Sandoval on Madam Secretary and Che Diaz on And Just Like That... Reports surfaced in February that Rami­rez won't return for And Just Like That... Season 3.